Potential Advantages

There are significant limitations to the current therapies for treating a range of tissue and organ abnormalities, and there is a clear need for approaches that are safer, more effective and cost-efficient.

Tengion's technology has the potential to offer several major advantages over current best practice. Tengion neo-organs and tissues have the potential, once approved and commercially available, to:

• Regenerate native function and structure
• Avoid the risk of organ rejection
• Eliminate the burden and costs of immunosuppression
• Reduce or eliminate other adverse effects of existing procedures
• Provide meaningful clinical safety and efficacy advances versus existing alternatives
• Shorten surgical and recovery time
• Potentially reduce healthcare costs for organ failure while improving medical outcomes
• Improve quality of life for patients and their families