For immediate release

Tengion to Present at the Piper Jaffray 20th Annual Healthcare Conference

Contact: Gary Sender
Chief Financial Officer
Tengion, Inc.
gary.sender@tengion.com

EAST NORRITON, PA, November 25, 2008—Tengion Inc., a clinical stage regenerative medicine company focused on the development of neo-organs and neo-tissues, today announced that Steven Nichtberger, M.D., President and Chief Executive Officer of Tengion, will present at the Piper Jaffray 20th Annual Healthcare Conference on Tuesday, December 2, 2008 at 9:50 a.m. EST at The Palace Hotel in New York City, New York.

About Tengion
Tengion, a clinical stage regenerative medicine company, focuses on developing, manufacturing and commercializing human neo-organs and neo-tissues using our Autologous Organ Regeneration Platform™. Tengion uses biocompatible materials and a patient's own (autologous) cells to create neo-organs or neo-tissues that are designed to catalyze the body's innate ability to regenerate.  Tengion's product candidates may ultimately address the most critical problems facing organ and tissue failure patients, enabling people to lead healthier lives without donor transplants or the side effects of related therapies.